Chronopharmacology of aspirin: administration-time dependent effects on blood pressure in women at high risk for preeclampsia
نویسندگان
چکیده
منابع مشابه
Administration time-dependent effects of aspirin in women at differing risk for preeclampsia.
This study extends previous results on the effects of low-dose aspirin on blood pressure in pregnant women at differing risk of developing hypertension in pregnancy and who received aspirin at different times according to their rest-activity cycle. A double-blind, randomized, placebo-controlled trial was conducted in 240 pregnant women randomly assigned to 1 of 6 groups according to treatment (...
متن کاملAdministration time-dependent influence of aspirin on blood pressure in pregnant women.
This study prospectively investigates the potential influence of low-dose aspirin on blood pressure in pregnant women who were at a higher risk of developing preeclampsia than that of the general obstetric population and who received aspirin at different times of the day according to their rest-activity cycle. A double-blind, randomized, controlled trial was conducted in 341 pregnant women (181...
متن کاملAdministration time-dependent effects of aspirin on blood pressure in untreated hypertensive patients.
Previous studies on the potential influence of aspirin on blood pressure have not taken into consideration the chronopharmacological effects of nonsteroidal anti-inflammatory drugs. This pilot study investigates the effects of aspirin on blood pressure in untreated hypertensive patients who received aspirin at different times of the day according to their rest-activity cycle. We studied 100 unt...
متن کاملcomparison between aspirin and placebo on the mean of 24 hour blood pressure in pregnant women at preeclampsia risk, a double blind randomized controlled clinical trial
background gestational hypertension is one of the three common causes of maternal death. this study was designed to compare the effects of aspirin and placebo on 24 hour blood pressure mean in women at risk of preeclampsia in two different diurnal times to prevent preeclampsia. methods sixty four women who were at risk of gestational hypertension were recruited to be included in the study using...
متن کاملAdministration time-dependent effects of combination therapy on ambulatory blood pressure in hypertensive subjects.
The aim of this study was to explore the influence of combination therapy in different administration time on antihypertensive efficacy and blood pressure variability in patients with essential hypertension. A total of 86 patients with stage II to III essential hypertension were randomly divided into 4 groups: taking indapamide and losartan potassium together in the morning or in the evening 2 ...
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ژورنال
عنوان ژورنال: American Journal of Hypertension
سال: 2002
ISSN: 0895-7061
DOI: 10.1016/s0895-7061(02)02314-2